Why women gain weight after menopause
CL Society 226: Woman with mobile phone by francisco_osorio
License (according to Flickr): Attribution License
License (according to Flickr): Attribution License
Many women find they load on the pounds more quickly than guys do as they get older, and a brand-new study on mice may help describe why. After menopause, the activity of a particular enzyme associateded with fat manufacturing -- called Aldh1a1-- boosts, the researchers said. The enzyme is found in mice in addition to people. During the study, female mice that ate a high-fat diet had more Aldh1a1 activity and made and stored more visceral fat (fat around the abdominal areas ) than did male mice who ate a high-fat diet. By contrast, female mice remained lean on a high-fat diet if they had actually been genetically engineered to lack the enzyme. The female hormone estrogen appears to suppress Aldh1a1 activity. This might imply that more youthful women, who have high levels of estrogen, are shielded against the enzyme's undesirable impacts.
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Ouliana Ziouzenkova
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HealthCondition: obesity
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HealthCondition: Diabetes
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Organization: Ohio State University
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- diabetes
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Why women gain weight after menopause
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Many women find they pack on the pounds more easily than men do as they get older, and a new study on mice may help explain why
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