Study links milk-producing protein to aggressive breast cancer | Reduction

Study links milk-producing protein to aggressive breast cancer

Excerpt:

The discovery that a protein which triggers milk production in women may also be responsible for making breast cancers aggressive could open up new opportunities for treatment of the most common and deadliest form of cancer among women. "The discovery opens up new avenues for therapy and for designing new markers that can predict response to therapy."- Lead author Professor Chris Ormandy from the Garvan Institute of Medical Research in Sydney Found in all breast cells, the protein ELF5 tries to activate milk production even in breast cancer cells, which does not work and then makes the cancer more aggressive, according to scientists in Australia and Britain. "The discovery opens up new avenues for therapy and for designing new markers that can predict response to therapy," said lead author Professor Chris Ormandy from the Garvan Institute of Medical Research in Sydney. In 2008, Ormandy's work linked ELF5 to milk production.

Concepts:

Oncology Cancer Breast cancer Estrogen Chemotherapy Metastasis Neoplasm Tumor

People:

Professor Chris Ormandy

Overall Sentiment: 0

Relevance: 0.908846

Sentiment	Quote
-0.237993	"Cancer cells can't respond properly (to ELF5), so they ... acquire some characteristics ... that make the disease more aggressive and more refractory (resistant) to treatment with existing therapies," Ormandy said ...
-0.0150279	"What we have shown in this paper is high ELF5 tumors are dependent on ELF5 for their proliferation and if we block ELF5 in high ELF5 tumors, we will block proliferation and that will treat the tumor," Ormandy said. ...
0.413828	"If we can develop a drug that targets ELF5, it will be very useful for that group of women," he said. ...
Sentiment Stats:	Number of Quotes: 3 Aggregate Sentiment: 0.1608071 Mean: 0.053602366666667 Standard Deviation: 1

Key:

• Aggregate Sentiment is meant to be an indicator of an individual's overall sentiment.
• The Mean is meant to be an indicator of an individual's average comment sentiment.
• The Standard Deviation, when there are enough quotes, will indicate an individual's consistency of sentiment (i.e. a Standard Deviation of 0 would mean they were very consistent in their sentiment and 1 would mean they were very inconsistent).

Note that quote stats are likely to be meaningless beyond the aggregate score due to the tiny sample size. However, they are always provided just in case you find something useful there.

Additional Info:

HealthCondition: breast cancer

Overall Sentiment: -0.0948985

Relevance: 0.653924

Disambiguation: DiseaseOrMedicalCondition | CauseOfDeath | RiskFactor | DiseaseReferences:

• Breast cancer: dbpedia
• Breast cancer: freebase

HealthCondition: cancers

Overall Sentiment: -0.467547

Relevance: 0.427863

Disambiguation: FieldOfStudy | DiseaseOrMedicalCondition | CauseOfDeath | DiseaseCause | MedicalSpecialty | RiskFactor | DiseaseReferences:

• Cancer: dbpedia
• Cancer: freebase
• Cancer: opencyc

HealthCondition: breast cancers

Overall Sentiment: 0.0199183

Relevance: 0.383862

Tags Details

Source Site: Study links milk-producing protein to aggressive breast cancer

Provided Title:

Study links milk-producing protein to aggressive breast cancer

Webpage Provided Keywords:

• Australia
• Biology
• breast cancer
• britain
• chemotherapy
• common
• link
• milk
• Sydney

Provided Desc:

The discovery that a protein which triggers milk production in women may also be responsible for making breast cancers aggressive could open up new opportunities for treatment of the most common and deadliest form of cancer among women

Data Sources

Full Content: http://feeds.foxnews.com/~r/foxnews/health/~3/7M9zNFATLnU/

Source